Article ID Journal Published Year Pages File Type
2743516 Anaesthesia & Intensive Care Medicine 2008 4 Pages PDF
Abstract

Drug elimination is the irreversible removal of drug from the body. In order to discuss the process, it is necessary to understand how the body handles drugs with a description of hepatic, renal and pulmonary clearance, as well as some of the other less common routes of elimination. Knowledge of first-pass metabolism along with discussion of the various disease states affecting elimination processes will allow better prediction of pharmacokinetics in practice.

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