Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2754592 | Clinical Lymphoma Myeloma and Leukemia | 2013 | 4 Pages |
Abstract
Epidemiologic studies provide an insight into the etiology of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia, which indicates that repetitive immune stimulation and genetic factors play an important role. Here, the current understanding on the causes of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia are reviewed. Recent studies of the literature are discussed, and future population-based studies are proposed to further elucidate the molecular mechanisms that underlie these associations. Finally, the clinical implications of these data are outlined, and perspectives on clinical follow-up and counseling are provided.
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Authors
Elisabet E. Manasanch, Sigurdur Y. Kristinsson, Ola Landgren,