Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2762447 | Journal of Clinical Anesthesia | 2014 | 5 Pages |
Abstract
Angelman syndrome arises by one of 4 genetic mechanisms. Patients often have craniofacial abnormalities, vagal hypertonia, skeletal muscle atrophy or underdevelopment, a history of seizure disorders, and pharmacodynamic unpredictability. Its pathogenesis, clinical manifestations, diagnosis and treatment options, and perioperative anesthetic considerations are presented.
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Authors
Cara M. Bevinetto, Alan D. Kaye,