Article ID Journal Published Year Pages File Type
2763346 Journal of Clinical Anesthesia 2011 5 Pages PDF
Abstract

Study ObjectiveTo evaluate the effect of clonidine when added to local anesthetics on duration of postoperative analgesia during retrobulbar block.DesignProspective, randomized controlled trial.SettingOperating room and Postanesthesia Care Unit of a university-affiliated hospital.Subjects80 ASA physical status 1, 2, and 3 patients undergoing vitreoretinal surgery with or without scleral buckling.InterventionsPatients in the control group (n = 40) received a retrobulbar block with 4.5 mL of lidocaine-bupivacaine and 0.5 mL of saline. Clonidine group patients (n = 40) received 4.5 mL of lidocaine-bupivacaine and 0.5 μg/kg of clonidine in a 0.5 mL volume.MeasurementsThe time to first analgesic request, frequency of postoperative pain, and number of postoperative analgesic requests per patient were assessed.Main Results37 patients in the control group (92.5%) versus 24 patients (60%) in the clonidine group reported pain postoperatively (P = 0.001), with a shorter time to first analgesic request noted in the control group (4.9 ± 3 vs 11.9 ± 5.3 hrs; P < 0.001). The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001].ConclusionsThe addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.

Related Topics
Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Authors
, , , , , , , ,