Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2763852 | Journal of Clinical Anesthesia | 2010 | 5 Pages |
Abstract
The case of an 18 year-old double-lung transplant recipient recovering from acute respiratory distress syndrome who developed repeated episodes of bradycardia and asystole (maximum duration: 10 sec) during dexmedetomidine administration is presented. Increased baseline vagal tone, paroxysmal coughing spells, and opioid administration were likely contributors to the episodes. Discontinuation of the drug restored regular sinus rhythm. Double-lung transplant recipients may be at especially increased risk for this phenomenon as a result of changes in the autonomic innervation of the heart.
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Authors
Xiaopeng Zhang, Ulrich Schmidt, John C. Wain, Luca Bigatello,