| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2767161 | Regional Anesthesia and Pain Medicine | 2007 | 8 Pages |
Abstract
MgSO4 coadministered with amide-type LAs shortened the duration of sciatic-nerve block in rats. Therefore, it does not seem to be useful as an adjuvant for peripheral-nerve block. The mechanism of this observed antagonism is unclear but appears to be independent of the action of LAs and MgSO4 at the LA receptor within the Na+ channel.
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Authors
Yu-Chun M.D., Chia-Ying M.S., Philipp M.D., Chi-Fei M.D., Jen-Kun M.D., Ph.D., Chien-Chuan M.D., Ging Kuo Ph.D., Peter M.D.,