Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2768040 | Revista Colombiana de Anestesiología | 2011 | 11 Pages |
Abstract
The therapeutic combination of the μ opioid receptor agonists with inhibitors of the norepinephrine reuptake have become more popular recently as an alternative to treat the mechanisms responsible for neuropathic pain. However, even though the inhibitors of the norepinephrine reuptake are well tolerated, their analgesic efficacy is usually unsatisfactory, and opioids usually have tolerability problems; the recent introduction of tapentadol, which combines in the same molecule both mechanisms of action can represent a novel, improved and efficient alternative for analgesia.
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Authors
Mario Andrés Leotau RodrÃguez,