Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2769555 | Revista Española de Anestesiología y Reanimación | 2008 | 6 Pages |
Abstract
The onset time of a neuromuscular blocker is linked to its effect and its permeability is linked to the size of its molecules or the molar potency, which is dose-dependent. In the case of atracurium, this correlation was poor and not significant. This finding coincides with those of other authors, who found that atracurium was distant from the regression line for equipotent quantities of different neuromuscular blockers. Substituting onset time with speed of action, however, made it possible to establish a strong and significant correlation. Our results suggest that the speed of action of atracurium depends on the size of its molecule.
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Authors
D. (Doctor en Ciencias Médicas. M.T.S.V.A. - M.T.S.V.C. - M.H.S.V.U.),