Article ID Journal Published Year Pages File Type
2770268 Revue Française d'Allergologie et d'Immunologie Clinique 2007 4 Pages PDF
Abstract
Among these, chronic cough deserves to be considered apart. The onset of asthmatic manifestations, exacerbation of previously existing asthma, and perpetuation of inflammatory phenomena appear to occur in children who are predisposed. The pathophysiology of associated bronchial hyperreactivity brings on a cascade of inflammatory mechanisms which include a number of cytokines. Use of macrolides for a prolonged period is justified in certain cases with chronic cough or with asthma that is poorly controlled with standard therapy.
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