| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2772202 | Techniques in Regional Anesthesia and Pain Management | 2012 | 4 Pages |
Abstract
Severe postoperative pain and wound hyperalgesia, a clinical sign of central sensitization, are risk factors for the development of chronic postsurgical pain. This article describes the neuronal changes that surgical pain and possibly high opioid doses cause in the central nervous system. It also relates how regional anesthesia might oppose these changes and block both the pain sensitization and the pain chronification following surgery.
Keywords
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Anesthesiology and Pain Medicine
Authors
Laurent Bollag, Philippe Richebé,