The interdisciplinary management of complex regional pain syndrome

Complex regional pain syndrome is an ill-defined disorder typified by disproportional pain to the inciting insult in a variable setting of vasomotor and autonomic changes. The exact etiology remains unclear but likely involves augmented cytokine release affecting both peripheral and central nervous systems with concomitant psychosocial intricacies. Management of complex regional pain syndrome should encompass a systematic, interdisciplinary approach including physical and occupational therapy, psychological interventions, and oral analgesics. A thorough diagnostic evaluation should be completed before pursuing invasive treatment options, and these should be considered only in patients experiencing difficulty in progressing through a multimodal program. Collaborative therapy among a multitude of specialties should aim to facilitate reanimation and functional restoration of the affected limb.