Biología molecular, epidemiología y clasificación de los tumores neuroendocrinos gastroenteropancreáticos (TEGEP)

The incidence of GEP endocrine tumors is less than 2.2/100,000 inhabitants/year. These tumors are more frequent in women and in people of color. The most frequent localization is gastrointestinal followed by the pulmonary area. Although most of these tumors are sporadic, they can be associated with some hereditary syndromes. In these cases, tumor progression is slower, which translates into longer survival than in sporadic tumors. The general classification of GEP endocrine tumors includes three categories: well-differentiated endocrine tumors - which in the case of pancreatic tumors are divided into benign tumors and tumors of uncertain behaviour - well differentiated endocrine carcinomas, and poorly differentiated endocrine carcinomas.