Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2774768 | Endocrinología y Nutrición | 2006 | 5 Pages |
Abstract
We present the case of a 56-year-old woman who, 5 years after receiving a diagnosis of unilateral adrenal pheochromocytoma and primary hyperparathyroidism, was diagnosed with acromegaly caused by a growth hormonesecreting pituitary adenoma. No germ-line mutations in RET, VHL and MEN-1 gene were detected. Medullar thyroid carcinoma was also ruled out. Therefore, the present case shows coexistence of a tumor characteristic of MEN 2 syndrome (pheochromocytoma) with a growth hormone-secreting pituitary tumor characteristic of MEN 1 syndrome and primary hyperparathyroidism, which can be observed in both multiple endocrine neoplasia syndromes, but without germline mutations in RET, VHL and MEN-1.
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Authors
Arturo Lisbona Gil, Mercedes Robledo, AsÃs Fernández Riestra, César Alonso RodrÃguez,