| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2778130 | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | 2007 | 7 Pages |
Abstract
The cellular localization of prostaglandin E2 receptors (EP) and their corresponding transcripts were investigated in human gastric and vascular tissues. A strong staining of the EP3 receptor on the gastric glands, mucous cells, media of the mammary and pulmonary arteries was observed by immunohistochemistry. We identified a new mRNA splice variant of the EP3 gene in human gastric fundic mucosa, mammary artery and pulmonary vessels. This EP3-Ic transcript contains exons 1, 2, 3, 5 and 6 of the EP3 gene and should be translated in the EP3-I isoform. In addition, the EP3-Ib, EP3-II, EP3-III, EP3-IV and EP3-e mRNAs were detected in these tissues.
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Authors
L. Kotelevets, N. Foudi, L. Louedec, A. Couvelard, E. Chastre, X. Norel,