Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2779535 | Bone | 2012 | 10 Pages |
Abstract
⺠Marrow ablation in BSP knockout mice: less medullary bone, resorbed more slowly. ⺠Lower levels of markers for mature osteoblasts and active osteoclasts in mutants. ⺠PTH maintained the medullary bone of wild type but not BSPâ/â marrow ablated mice. ⺠PTH increased formation in both genotypes, reduced osteoclasts only in wild type. ⺠BSP is crucial for primary bone formation, modeling and response to PTH.
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Authors
Ndéye Marième Wade-Gueye, Maya Boudiffa, Arnaud Vanden-Bossche, Norbert Laroche, Jane E. Aubin, Laurence Vico, Marie-Hélène Lafage-Proust, Luc Malaval,