Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2779689 | Bone | 2010 | 9 Pages |
Abstract
The 3DCT method was highly reproducible and provided high precision measurements of bone size in the rat enabling identification of new sex- and cross-specific loci. The QTLs on chr 1 indicate potential genetic association between bone-related phenotypes and traits affecting type-2 diabetes. The results illustrate the complexity of the genetic architecture of bone size phenotypes and demonstrate the importance of complementary methods for bone analysis.
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Authors
Sofia Lagerholm, Hee-Bok Park, Holger Luthman, Mats Nilsson, Fiona McGuigan, Maria Swanberg, Kristina Ã
kesson,