Article ID Journal Published Year Pages File Type
2782451 Bone 2007 7 Pages PDF
Abstract

The goal of this review is to examine some of the metabolic features of the maturing chondrocyte within the epiphyseal growth plate. The energy status of the tissue is examined in light of the energy needs of the tissue and the availability of oxygen. The role of HIF, PHDs and other proteins concerned with transduction of the oxemic response is considered and related to chondrocyte survival in a complex extracellular matrix.

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Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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