Article ID Journal Published Year Pages File Type
278337 International Journal of Solids and Structures 2013 8 Pages PDF
Abstract

Multilayered gels play an important role in biomedical engineering as drug delivery vehicles, replacement tissues and bio-mimetic substrates for cell cultures. It has been established that the gel elasticity strongly influences the intended functionalities. In view of this, second-order elastic solutions for the stresses and displacements in cylindrical multilayered hydrogels subjected to various dilatation profiles are developed in this paper. The results emphasize the importance of nonlinearity in gel mechanics, and suggest the possibility of a rational selection of layer elasticities, layer thicknesses and dilatation profiles for improved mechanical responses such as maximum/minimum swelling and multiaxial stress states.

► This paper develops solutions for a composite gel subjected to a dilatation. ► It analyzes a multilayered cylinder in the framework of second-order elasticity. ► The results emphasize the role of nonlinearity, layer dissimilarity and dilatation profile. ► The results can be applied to bio-environment design in tissue engineering and stem cell technology.

Related Topics
Physical Sciences and Engineering Engineering Civil and Structural Engineering
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