Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2784902 | Current Opinion in Genetics & Development | 2010 | 6 Pages |
Abstract
Over four decades ago, the first oscillations in metabolism in yeast cells were reported. Since then, multiple forms of oscillatory behavior have been observed in yeast grown under a variety of continuous culturing environments. The remarkable synchrony of cells undergoing such oscillations has made them ideal subjects for investigation using systems-based approaches. Herein, we briefly summarize previous work on the characterization of such oscillations using systems approaches, and present the long-period, Yeast Metabolic Cycle as an excellent model system for deciphering the temporal organization of fundamental cellular and metabolic processes at unprecedented resolution.
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Authors
Sunil Laxman, Benjamin P Tu,