Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2785087 | Current Opinion in Genetics & Development | 2010 | 10 Pages |
Abstract
In this review we discuss both gene expression and protein localization changes of polarity proteins in carcinoma. We highlight the importance of protein mislocalization and its possible role in cancer. We also discuss the emerging role of polarity proteins as regulators of proliferation, apoptosis, tissue polarity, epithelial–mesenchymal transition, in addition to their known role in cell junction biogenesis.
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Authors
Ling Huang, Senthil K Muthuswamy,