Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2785090 | Current Opinion in Genetics & Development | 2010 | 7 Pages |
Abstract
Epidemiological and experimental data suggest a close connection between inflammation and tumorigenesis. Solid tumors are typically infiltrated with immune cells and inflammation impacts most, if not all, stages of tumorigenesis. Molecular and cellular pathways, which connect inflammation and cancer, have emerged as attractive targets for prevention and therapy. In this review we discuss general mechanisms and concepts of cancer promoting inflammation.
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Authors
Sergei I Grivennikov, Michael Karin,