Article ID Journal Published Year Pages File Type
2785173 Current Opinion in Genetics & Development 2007 7 Pages PDF
Abstract

The antigen receptor genes are organized into distinct DNA elements that encode the variable (V), diversity (D) and joining (J) regions. It is now well established that the rearrangement of antigen receptor genes is regulated by developmental-specific modulation of chromatin structure. Further studies involving statistical mechanics should provide physical insight into the physical mechanisms that underlie the association of antigen receptor gene segments.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
Authors
,