| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2785395 | Current Opinion in Genetics & Development | 2006 | 4 Pages |
Abstract
Sex determination in mammals is based on a genetic cascade that controls the fate of the gonads. Gonads will then direct the establishment of phenotypic sex through the production of hormones. Different types of sex reversal are expected to occur if mutations disrupt one of the three steps of gonadal differentiation: formation of the gonadal primordia, sex determination, and testis or ovary development.
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Authors
Giovanna Camerino, Pietro Parma, Orietta Radi, Stella Valentini,