Article ID Journal Published Year Pages File Type
2786597 International Journal of Developmental Neuroscience 2010 9 Pages PDF
Abstract
▶ Spinal cord injury induces P2Y2 mRNA expression. ▶ Trauma to the spinal cord upregulates the un-glycosylated form of the P2Y2 receptor. ▶ Contusion to the cord downregulates the glycosylated form of the P2Y2 receptor. ▶ P2Y2 receptor is expressed in neurons and glial cells of the injured spinal cord. ▶ The spatio-temporal pattern of P2Y2 gene expression after injury suggests a role in the pathophysiology response generated after trauma.
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