| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2792898 | Cell Metabolism | 2012 | 6 Pages |
Abstract
While originally described as DNA damage repair agents, recent data suggest a role for poly(ADP-ribose) polymerase (PARP) enzymes in metabolic regulation by influencing mitochondrial function and oxidative metabolism. Here we review how PARP activity has a major metabolic impact and the role of PARP-1 and PARP-2 in diverse metabolic complications.
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Authors
Péter Bai, Carles Cantó,