| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2794399 | Cytokine | 2012 | 9 Pages |
Abstract
⺠Liver TAFI expression increases in acute phase in mice but mechanism is unknown. ⺠We demonstrate that mouse TAFI transcription is increased by TNFα. ⺠TNFα acts through an NFκB site in the mouse promoter that is absent in human. ⺠Our findings rationalize the species-specific response of TAFI levels to endotoxin.
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Authors
Mathieu Garand, Joellen H.H. Lin, Ceredwyn E. Hill, Branislava Zagorac, Marlys L. Koschinsky, Michael B. Boffa,