| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2795073 | Cytokine | 2010 | 7 Pages |
Abstract
Peripheral blood mononuclear cells (PBMC) of breast cancer patients show altered prolactin (PRL)-induced proinflammatory response and express short form of prolactin receptor (PRL-R), besides secreting elevated level of interleukin (IL)-10 than that of the normal counterparts. IL-10 depleted the functional long form of PRL-R mRNA and protein, expressed PRL-R (SF) mRNA and blocked the PRL response found in normal individuals, which could be a mechanism to suppress the proinflammatory immune responses during malignancy.
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Authors
Sonali Paul, Amlan Biswas, Krittika Sasmal, Subhadeep Mukherjee, Tapas Biswas, Ratna Biswas,