| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2795538 | Cytokine | 2008 | 7 Pages |
Abstract
The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the release of critical proinflammatory cytokines that are necessary to activate potent immune responses. LPS/TLR4 signaling has been intensively studied in the past few years. Here we review molecules involved in TLR4-mediated signaling, including players that are involved in the negative regulation of this important pathway.
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Authors
Yong-Chen Lu, Wen-Chen Yeh, Pamela S. Ohashi,