Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2796191 | Diabetes Research and Clinical Practice | 2015 | 4 Pages |
Abstract
•Lobeglitazone is a novel PPAR-γ agonist containing the TZD motif.•Lobeglitazone is mainly excreted in feces, thereby reducing the risk of bladder cancer.•Lobeglitazone showed a favorable balance of efficacy and safety in patients with type 2 diabetes during 52 weeks.
We aimed to assess the safety and efficacy of lobeglitazone in patients with type 2 diabetes over 52 weeks through 28-week extension study. Clinical benefits in terms of glycemic and lipid control were maintained for 52 weeks. Lobeglitazone showed a favorable balance of efficacy and safety during the extension study.
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Authors
Sun Hwa Kim, Sin Gon Kim, Doo Man Kim, Jeong-Taek Woo, Hak Chul Jang, Choon Hee Chung, Kyung Soo Ko, Jeong Hyun Park, Yong Soo Park, Sang Jin Kim, Dong Seop Choi,