Article ID Journal Published Year Pages File Type
2796191 Diabetes Research and Clinical Practice 2015 4 Pages PDF
Abstract

•Lobeglitazone is a novel PPAR-γ agonist containing the TZD motif.•Lobeglitazone is mainly excreted in feces, thereby reducing the risk of bladder cancer.•Lobeglitazone showed a favorable balance of efficacy and safety in patients with type 2 diabetes during 52 weeks.

We aimed to assess the safety and efficacy of lobeglitazone in patients with type 2 diabetes over 52 weeks through 28-week extension study. Clinical benefits in terms of glycemic and lipid control were maintained for 52 weeks. Lobeglitazone showed a favorable balance of efficacy and safety during the extension study.

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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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