| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2796765 | Diabetes Research and Clinical Practice | 2013 | 4 Pages |
Abstract
A potential adverse effect of dipeptidyl peptidase-4 inhibitors (DPP-4i) on the pancreas remains controversial. We evaluated the DPP-4i effects on pancreatic amylase and lipase activity in patients with type 2 diabetes. These enzymes were slightly but significantly increased, suggesting DPP-4i cause a low-grade inflammatory change in the exocrine pancreas.
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Authors
Hirotake Tokuyama, Harukiyo Kawamura, Masaki Fujimoto, Kazuki Kobayashi, Mie Nieda, Tetsuya Okazawa, Minoru Takemoto, Fumio Shimada,