Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2797093 | Diabetes Research and Clinical Practice | 2012 | 5 Pages |
Abstract
We tested the association of TCF7L2 variants with type 2 diabetes (T2DM) in 691 Lebanese people and 919 controls. rs7901695, rs4506565, rs7903146, rs12243326, rs7895340, and rs12255372 minor allele frequencies were higher in T2DM. Haplotype analysis (rs7901695–rs4506565–rs7903146–rs12243326–rs7895340–rs11196205–rs12255372) identified positively- (2122112, 2222222) and negatively- (1111111) T2DM-associated haplotypes. TCF7L2 is a common T2DM candidate gene in Lebanese people.
Keywords
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Authors
Rita Nemr, Amira Turki, Akram Echtay, Ghadeer S. Al-Zaben, Hoda S. Daher, Noha A. Irani-Hakime, Sose H. Keleshian, Wassim Y. Almawi,