Article ID Journal Published Year Pages File Type
2799138 Diabetes Research and Clinical Practice 2006 4 Pages PDF
Abstract

ObjectiveTo determine the occurrence of persistent impaired glucose tolerance (IGT) (two times OGTT positive) and to compare the physical and clinical characteristics with subjects having transient IGT or diabetes.Research design and methodsNondiabetic subjects aged 35–55 years were screened (n = 10,839, M:W 8667:2172) using 2 h capillary blood glucose. IGT was diagnosed in 1332 (12.3%). Among them, 1025 (77%) responded for a second OGTT and 531 subjects (51.8%) had persistent IGT. Biochemical, demographic and anthropometric characteristics were compared among the normal (NGT, 30.1%), IGT and diabetic subjects (DM, 18%) at second GTT.ResultsAll had similar age. BMI, waist circumference and body fat percentage were lower in NGT than in IGT and diabetes. IGT and diabetes had similar characteristics. Family history of diabetes was the highest in persistent IGT.ConclusionAmong the screened subjects, 1 in 20 had persistent IGT. Subject with persistent IGT had higher rates of risk factors for diabetes, such as high BMI, waist circumference and body fat percentage.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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