Current genomic editing approaches in avian transgenesis

The chicken was domesticated from Red Jungle Fowl over 8000 years ago and became one of the major food sources worldwide. At present, the poultry industry is one of the largest industrial animal stocks in the world, and its economic scale is expanding significantly with increasing consumption. Additionally, since Aristotle used chicken eggs as a model to provide remarkable insights into how life begins, chickens have been used as invaluable and powerful experimental materials for studying embryo development, immune systems, biomedical processes, and hormonal regulation. Combined with advancements in efficient transgenic technology, avian models have become even more important than would have been expected.

► Chicken embryos are an excellent model for studying developmental endocrinology. ► Transgenic techniques will provide powerful tools for studying avian endocrinology. ► The specific genomic editing will extend our knowledge of endocrinological mechanisms.