Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2800882 | General and Comparative Endocrinology | 2011 | 10 Pages |
Abstract
⺠Secretion from Tilapia prolactin cells was followed as membrane capacitance (Cm) increase by perforated patch clamping. ⺠Depolarizing pulses stimulated Cm increases (ave 7.2 fF/s, n = 50) and were reversibly blocked by 0 Ca2+ or Cd2+, not by TTX. ⺠Cm increases in hyposmotic perfusate were much slower (ave 0.68 fF/s, n = 17). ⺠Hyposmotic responses were reduced by Ca2+-free but not by Cd2+ saline. ⺠PRL cells secrete hormone using two distinct mechanisms; both are mediated by Ca2+.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Shenghong Xu, Takeshi Shimahara, Ian M. Cooke,