Article ID Journal Published Year Pages File Type
2801282 General and Comparative Endocrinology 2010 7 Pages PDF
Abstract
► This is the first report of the cloning and expression of a reptilian D3 cDNA. ► Present results support the proposal that hepatic D3 in adult vertebrates plays a sentinel role in avoiding an inappropriate overload of exogenous T3 secondary to feeding in those species that devour thewhole prey. ► As in other D1s and D3s, the hinge region of PdD3 is rich in prolines, an observation that suggests that the presence of proline residues could be a specific feature of IRD-catalyzing enzymes.
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