Article ID Journal Published Year Pages File Type
2802774 Growth Hormone & IGF Research 2011 8 Pages PDF
Abstract
Our observations indicate that the stimulating effect of NHS is completely dependent on IGF-I receptor signaling transduction and that IGF-I stimulates DNA synthesis in prostate cancer cells in strong synergy with other serum factors. We speculate that the role of other serum factors could explain the discrepancy between the results observed in different animal models to study the function of IGF-I in prostate cancer.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Attenuation of IGF-I receptor signaling inhibits serum-induced proliferation of prostate cancer cells
Authors
, , , ,