Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2803010 | Growth Hormone & IGF Research | 2010 | 6 Pages |
Abstract
Despite marginal reductions in total IGF-I and -II, bioactive and free IGF-I declined markedly during and after HD. This is likely a consequence of the increase in IGFBP-1, sequestering free IGF-I, and reducing bioactive IGF-I. Based on the present data we hypothesize that the catabolism induced by HD is in part related to the observed reductions in bioactive IGF-I.
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Authors
Per Ivarsen, Jian-Wen Chen, Ida Tietze, Jens Sandahl Christiansen, Allan Flyvbjerg, Jan Frystyk,