Article ID Journal Published Year Pages File Type
2803266 Growth Hormone & IGF Research 2008 10 Pages PDF
Abstract
Our novel findings provide evidence for in vivo activity of rhIGFBP-3 against lung and colon tumor models and reveal new insight into its interaction with chemotherapeutic drugs. The antitumor effects of rhIGFBP-3 are associated with a downregulation of AKT signaling.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Recombinant human insulin-like growth factor-binding protein 3 inhibits tumor growth and targets the Akt pathway in lung and colon cancer models
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