Article ID Journal Published Year Pages File Type
2804369 Journal of Diabetes and its Complications 2013 7 Pages PDF
Abstract

Type 2 diabetes mellitus (T2DM) significantly increases morbidity and mortality from cardiovascular disease (CVD). Treatments for patients with T2DM have the potential to reduce cardiovascular (CV) risk. This review focuses on the potential of a new class of antidiabetic agents, the sodium glucose cotransporter 2 (SGLT2) inhibitors, to reduce CV risk in patients with T2DM through reductions in hyperglycemia, blood pressure (BP), and body weight. The results of clinical trials of SGLT2 inhibitors are summarized and discussed.

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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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