Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2804407 | Journal of Diabetes and its Complications | 2013 | 5 Pages |
Abstract
Optimal insulin therapy in mice and humans with type 1 diabetes causes iatrogenic hyperinsulinemia and subsequently promotes pro-inflammatory macrophage response independent of hepatic cholesterol-relevant CAD markers. The tight glycemic control in type 1 diabetes may thus increase the risk for atherogenesis via inflammation.
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Authors
May-Yun Wang, Xinxin Yu, Young Lee, S. Kay McCorkle, Gregory O. Clark, Suzanne Strowig, Roger H. Unger, Philip Raskin,