Article ID Journal Published Year Pages File Type
2805524 Metabolism 2013 6 Pages PDF
Abstract

ObjectiveTo examine maternal serum levels of retinol-binding protein-4 (RBP4) at 11–13 weeks’ gestation in normal and pathological pregnancies.MethodsSerum RBP4 at 11–13 weeks was measured in 480 singleton pregnancies, including 240 with normal outcome, 60 that subsequently developed preeclampsia (PE), 60 that developed gestational diabetes mellitus (GDM), 60 that delivered large for gestational age (LGA) neonates and 60 that delivered small (SGA) neonates. The values in each adverse pregnancy outcome group were compared to those of normal pregnancies.ResultsSerum concentration of RBP4 was not significantly different in women who subsequently developed PE (p = 0.925), or GDM (p = 0.074), or had pregnancies that led to delivery to SGA (p = 0.085), LGA (p = 0.332) neonates.ConclusionMaternal serum RBP4 in the first trimester is not significantly altered in pathological pregnancies.

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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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