| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2805967 | Metabolism | 2013 | 10 Pages |
Abstract
Our studies indicate that a humanized mouse model with human islet grafts could mimic the in vivo characteristics of human islets and could be a powerful tool for the evaluation of novel insulin secretagogues or other therapeutic agents that directly and/or indirectly target human β cells.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Jian Luo, Kathy Nguyen, Michael Chen, Than Tran, Jianqiang Hao, Bole Tian, Ingrid C. Rulifson, Ying Zhang, Lei Tian, Yu Zhang, Edwin Lopez, Daniel C.-H. Lin, Yingcai Wang, Zhihua Ma, Jonathan Houze, Zhiguang Guo,