Article ID Journal Published Year Pages File Type
2810115 Trends in Endocrinology & Metabolism 2016 4 Pages PDF
Abstract

Glucagon-like peptide (GLP)-1 receptor agonists enhance insulin secretion and may improve pancreatic islet cell function. However, GLP-1 receptor (GLP-1R) agonist treatment may have more complex, and sometimes deleterious, effects on beta cells. We discuss the concepts of beta cell protection versus exhaustion for different GLP-1R agonists based on recent data.

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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?
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