Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2810926 | Trends in Endocrinology & Metabolism | 2007 | 6 Pages |
Abstract
Polycystic ovary syndrome (PCOS) is an endocrinopathy that affects women of reproductive age. PCOS shares components with the metabolic syndrome and has broad health implications. Lipid abnormalities, including elevated low-density lipoprotein (LDL), triglyceride levels and decreased high-density lipoprotein (HDL), are often found in women with PCOS. It is clear that obesity, insulin resistance and hyperandrogenism coexist in PCOS, and have independent and interactive effects on dyslipidemia, although the mechanisms of these interactions remain elusive. Here, we review the types and pathophysiology of dyslipidemia associated with PCOS and its related conditions.
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Authors
Evanthia Diamanti-Kandarakis, Athanasios G. Papavassiliou, Stylianos A. Kandarakis, George P. Chrousos,