Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2813215 | Clínica e Investigación en Ginecología y Obstetricia | 2006 | 5 Pages |
Abstract
Both assays are useful for the detection of high-risk HPV in cervical scrapings. Unlike other authors, we found that the HC assay was more sensitive in detecting high-risk HPV. PCR has the advantage of identifying an exact genotype and mixed infections and is also useful for epidemiologic purposes. The most prevalent genotype in women with abnormal cytology was type 16 but the second most frequent genotype, type 53, was not found in women with cervical cancer and was therefore classified as «probably carcinogenic». The epidemiological importance of this genotype should be investigated with a view to including it in future vaccines.
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Authors
J. Chacón, M.L. Mateos, I. Sanz, M.D. Rubio, F. Baquero,