Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2814351 | European Journal of Medical Genetics | 2011 | 4 Pages |
Abstract
We report an adult male with 22q11.2 deletion syndrome and a germline BRCA2 mutation who developed T-cell monoclonal lymphoid proliferation involving the skin and a polyclonal proliferation of a retroperitoneal lymph node without any identifiable infectious and inflammatory causes. This is the first report of reactive lymphoid hyperplasia in the setting of co-occurrence of 22q11.2 deletion syndrome and a BRCA2 mutation. Further cases with a similar presentation should be reported and studies should be directed to identify the possible mechanisms involved.
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Authors
Aravindhan Veerapandiyan, Ivan Kingyue Chinn, Kelly Schoch, Kristin A. Maloney, Vandana Shashi,