| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2814641 | European Journal of Medical Genetics | 2007 | 6 Pages |
Abstract
A 27-year-old man was referred for chromosome analysis due to infertility caused by azoospermia. Chromosome analysis by conventional karyotyping, multicolour FISH (M-FISH) and multicolour banding (MCB) analysis revealed an apparently balanced translocation between chromosomes 1, 3, 9 and 14 as well as an additional inverted insertion of 3q material with a total of eight breakpoints. Due to the diversity of theoretically unbalanced products of meiotic recombination in this exceptional complex chromosomal rearrangement a successful result of assisted reproduction seems unlikely.
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Authors
Iris Bartels, Heike Starke, Loukas Argyriou, Simone M. Sauter, Barbara Zoll, Thomas Liehr,