Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2816920 | Gene | 2013 | 11 Pages |
•The sequences of key genes involved in lipid metabolism were cloned.•Tissue expression profiles of these genes were explored.•Correlations were observed between mRNA levels of some genes.
11 genes involved in lipid metabolism were cloned from liver of yellow catfish Pelteobagrus fulvidraco, including CPT 1A, CPT 1B, PPARα, PPARγ, SREBP-1, G6PD, 6PGD, FAS, acetyl-CoA ACCa, ACCb, and LPL. Phylogenetic analysis further identified these genes, and confirmed the classification and evolutionary status of yellow catfish. mRNA of all eleven genes was present in liver, muscle, mesenteric adipose, ovary and heart, but at varying levels. The present study will facilitate further studies on the regulation of lipid metabolism at the molecular level for the fish species.