Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2818763 | Gene | 2009 | 5 Pages |
Abstract
Using a direct miRNA cloning strategy we previously identified fourteen marsupial- or species-specific microRNAs in the marsupial species Monodelphis domestica. In the present study we examined each of the pre-miRNAs and their flanking sequences and demonstrate that half of these miRNAs evolved from marsupial-specific transposable elements. These findings reinforce the view that transposable elements are a previously unappreciated source of new, lineage-specific microRNAs.
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Authors
Eric J. Devor, Andrew S. Peek, William Lanier, Paul B. Samollow,