| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2820652 | Genomics | 2013 | 7 Pages |
The main objective of the present study was to reanalyse tomato expression data that was previously submitted to the Tomato Expression Database to dissect the resistance/defence genomic and metabolic responses of tomato to Phytophthora infestans under field conditions. Overrepresented gene sets belonging to chromosome 10 were identified using the Gene Set Enrichment Analysis, and we found that these genes tend to be located towards the end of the chromosome 10. An analysis of syntenic regions between Arabidopsis thaliana chromosomes and the tomato chromosome 10 allowed us to identify conserved regions in the two genomes. In addition to allowing for the identification of tomato candidate genes participating in resistance/defence in the field, this approach allowed us to investigate the relationships of the candidate genes with chromosomal position and participation in metabolic functions, thus offering more insight into the phenomena occurring during the infection process.
► Defence/resistance genes to P. infestans are preferentially located in chr. 10. ► Defence genes in tomato are located towards the chromosome ends. ► Identified defence/resistance genes are conserved between tomato and Arabidopsis. ► Defence/resistance genes against P. infestans have evolved in a clustered fashion.
